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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAYN All Species: 22.73
Human Site: S369 Identified Species: 62.5
UniProt: Q6UX15 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UX15 NP_849156.1 382 43108 S369 S P D Q M G R S K E S G W V E
Chimpanzee Pan troglodytes XP_508749 382 43098 S369 S P D Q M G R S K E S G W V E
Rhesus Macaque Macaca mulatta XP_001105695 382 43063 S369 S P D Q I G R S K E S G W V E
Dog Lupus familis XP_546529 503 54611 S490 S P D R M G R S K E S G W V E
Cat Felis silvestris
Mouse Mus musculus Q8C351 381 43181 S369 S P D R M G R S K E S G W V E
Rat Rattus norvegicus XP_576410 376 42696 S364 S P D R M G R S K E S G W V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510411 255 28425 I243 A N Q S T L W I S K N S R K E
Chicken Gallus gallus XP_001231435 275 30026 I263 P N Q S T L W I S K T P R K D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693396 388 44187 R374 L Q G R G S G R Y Y R D Q G W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.3 64.4 N.A. 83.7 79 N.A. 34.5 39 N.A. 50 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 98.1 69.3 N.A. 89.7 84.5 N.A. 47.3 50 N.A. 63.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 6.6 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 20 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 0 0 0 0 0 0 12 0 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 78 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 12 67 12 0 0 0 0 67 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 23 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 67 23 0 0 0 23 0 % K
% Leu: 12 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 23 0 0 0 0 0 0 0 0 12 0 0 0 0 % N
% Pro: 12 67 0 0 0 0 0 0 0 0 0 12 0 0 0 % P
% Gln: 0 12 23 34 0 0 0 0 0 0 0 0 12 0 0 % Q
% Arg: 0 0 0 45 0 0 67 12 0 0 12 0 23 0 0 % R
% Ser: 67 0 0 23 0 12 0 67 23 0 67 12 0 0 0 % S
% Thr: 0 0 0 0 23 0 0 0 0 0 12 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % V
% Trp: 0 0 0 0 0 0 23 0 0 0 0 0 67 0 12 % W
% Tyr: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _